Istani Reyla
- Name: Istani Reyla
- Species: Bajoran
- Gender: Female
- Prylar of the Bajoran faith (DS9 Novel: Avatar, Book One)
- c.2340s: Resident, Singha refugee camp (DS9 Novel: Avatar, Book One)
- Death: March 28, 2376; Deep Space 9 (DS9 Novel: Avatar, Book One)
- Murdered by Vedek Gamon Vell in an attempt at suppressing the release of the Ohalu prophecies (DS9 Novel: Avatar, Book One)