Rigelian fever
- Deadly disease first appearing late-13th century during forceable resettling of Kalar on Rigel VII (ENT Novel: Tower of Babel)
- Appeared due to crowded, unsanitary conditions leading to heightened levels of viral cross-propagation and mutation (ENT Novel: Tower of Babel)
- If left untreated, one of the deadliest known contagions (ENT: "Cold Station 12")
- Cure first developed 1370 (Tower of Babel Annotations)
- Treatment regimen derived from ryetalyn-based compound (Tower of Babel Annotations; TOS: "Requiem for Methusaleh"; TNG Novel: The Battle of Betazed)