Joseph Sisko
- Full Name: Joseph Sisko
- Born: New Orleans, United States of America, Earth
- Species: Human
- Gender: Male
- Wife: Sarah Sisko (2331 - 2336)
- Married August 2331 (DS9: "Images in the Sand")
- Died 2336 (DS9: "Images in the Sand")
- Wife: Rebecca Sisko ( - 2350s - )
- Died by 2372 (DS9: "Homefront")
- Son: Benjamin Sisko
- Daughter: Judith Sisko
- Son: Aaron Sisko
- Son: Samuel Sisko
- By 2332: Owner and chef, Sisko's Creole Kitchen, New Orleans, United States of America, Earth (STA Novel: Maker; DS9: "Homefront", "Paradise Lost", "Tears of the Prophets", "Image in the Sand")
- Death: February 2381 (TP Novel: Rough Beasts of Empire)