Mackenzie Calhoun
- Full Name: Mackenzie Calhoun
- Formerly known as: M'k'n'zy of Calhoun
- Born: c.2334; Calhoun, Xenex
- Species: Xenexian
- Gender: Male
- April 2354: Cadet, Starfleet Academy (NF Novel: Stone and Anvil)
- First Xenexian in Starfleet
- March 2376: Captain, commanding officer, Starfleet; USS Excalibur (DS9 Novel: Demons of Air and Darkness)