Life of unknown origin
- Life forms with no explicitly specified planet of origin
Animal
- Jacinnan racing cat (TNG Novel: The Buried Age)
- Noted for its speed (TNG Novel: The Buried Age)
- Osmotic eel (ENT: "Broken Bow", "Minefield", "Marauders", "Exile", "The Council", "Countdown", "Home")
- Seemingly consumes microorganisms and parasites in the blood symbiotically, while halting bloodflow, consuming small amounts of blood in the process (ENT: "Broken Bow", "Minefield", "Countdown"; ENT Novel: Uncertain Logic)
- Tumodian lamprey (ENT Novel: Uncertain Logic)
- Feeds on contaminants in blood symbiotically (ENT Novel: Uncertain Logic)
- Can serve as a natural form of hemodialysis as a result (ENT Novel: Uncertain Logic)
- Feeds on contaminants in blood symbiotically (ENT Novel: Uncertain Logic)
- Vghlar beetle (ENT Novel: Live by the Code)
- Can serve as natural vitamin supplement for humanoids (ENT Novel: Live by the Code)
- Vicarian razorback (DS9: "The Die is Cast"; DS9 Novel: Avatar, Book Two)
- Native to a world near Bajoran and Cardassian space
- Yurhaath (ENT Novel: Live by the Code)
- Bird-like species known to the Hurraait (ENT Novel: Live by the Code)
Plant
- Diomedian scarlet moss (TNG Novel: The Battle of Betazed)
- Draebidium calimus (TNG Novel: The Battle of Betazed)
- Flower similar to violets (TNG Novel: The Battle of Betazed)
- Shendurian stingvine (ENT Novel: Uncertain Logic)
- Bulbous yellow-green plant seemingly a blend of vine and cactus (ENT Novel: Uncertain Logic)
- Extremely pungent, sweet aroma (ENT Novel: Uncertain Logic)